Vitamin D: non-skeletal actions and rational use
نویسندگان
چکیده
منابع مشابه
Vitamin D: non-skeletal actions and rational use.
Recent years have witnessed a substantial increase in the number of seric determinations of vitamin D, in a worldwide basis. At Hospital das Clínicas of Faculdade de Medicina of Universidade de São Paulo that increase reached 700% over the last four years. Nevertheless there are many controversies on the literature about the role of vitamin D in conditions unrelated to the musculoskeletal syste...
متن کاملEvidence-based non-skeletal actions of vitamin D.
Vitamin D is a major regulator of mineral homeostasis through its action in the kidney, intestine, bone and parathyroid glands. On these tissues, its active form, calcitriol, acts by binding to a specific nuclear receptor that belongs to the steroid/thyroid hormone receptor family. This receptor, however, has also been identified in several additional human tissues. So, apart from its tradition...
متن کاملThe Non-Genomic Actions of Vitamin D
Since its discovery in 1920, a great deal of effort has gone into investigating the physiological actions of vitamin D and the impact its deficiency has on human health. Despite this intense interest, there is still disagreement on what constitutes the lower boundary of adequacy and on the Recommended Dietary Allowance. There has also been a major push to elucidate the biochemistry of vitamin D...
متن کاملVitamin D and Skeletal Aging
INTRODUCTION Vitamin D is required for intestinal absorption of dietary calcium and for normal mineralization of bone. It fulfills the classic definition of a vitamin because it is an essential nutrient provided by natural foodstuffs that is needed in minute amounts to prevent deficiency diseases. Dietary sources are plants, which photosynthesize ergocalciferol (vitamin D2), fatty fishes such a...
متن کاملNonclassic actions of vitamin D.
CONTEXT Vitamin D receptors are found in most tissues, not just those participating in the classic actions of vitamin D such as bone, gut, and kidney. These nonclassic tissues are therefore potential targets for the active metabolite of vitamin D, 1,25(OH)(2)D. Furthermore, many of these tissues also contain the enzyme CYP27B1 capable of producing 1,25(OH)(2)D from the circulating form of vitam...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Revista da Associação Médica Brasileira (English Edition)
سال: 2013
ISSN: 2255-4823
DOI: 10.1016/s2255-4823(13)70509-5